If gout is left untreated, attacks can become more common and may spread to new joints.Īttacks typically affect the joint at the base of the big toe and often start in the early hours of the morning. The attack usually settles after about five to seven days, but it can go on for longer.
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The skin over the joint often appears shiny and it may peel off as the attack settles.Īttacks usually come on very quickly, often during the night. Doctors describe the sudden development of symptoms as ‘acute’. But crystals can also appear under your skin and may even occur in your internal organs, such as the kidneys.ĭuring an attack of gout, the affected joint becomes: If urate levels stay too high, urate crystals can slowly form. They mainly occur in and around firm joint tissues, such as the cartilage. On any day, about three-quarters of the urate in our bodies comes from the breakdown of purines produced within our body, while only about a quarter comes from food and drink. As urate levels build up, your body gets rid of any extra through your kidneys and in your wee. But if your body makes too much urate, or your kidneys are unable to get rid of enough of it, then levels start to rise. While this can make attacks of gout more likely, it’s not the whole story. People used to think that gout was caused by overeating and drinking too much alcohol. We all have urate in our blood: this is normal and healthy. But if levels become too high it may cause gout. Purines are chemicals that are naturally created in our body, but they are also present in certain foods. Urate is created every day when our bodies break down purines. Gout occurs in people who have high levels of uric acid, also known as urate, in their blood. It’s more common in men and you’re more likely to get it as you get older. It’s the most common type of inflammatory arthritis.
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Gout is a painful form of arthritis caused by uric acid crystals that form in and around the joints.